Vitamin D and Calcium

Full Title: The Relationships of Vitamin D and Calcium Intakes to Nutrient Status Indicators and Health Outcomes

Expected Release Date: late 2009

Key Questions in relation to the Analytic Framework*

Select Figures 1 and 2 for diagrams of the Analytic Framework.

1. What is the effect of exposures on functional or clinical outcomes? (Curve 1 in diagram)
   1. What factors affect this relationship?
2. What is the effect of exposures on indicators of functional or clinical outcomes? (Curve 2 in diagram)
   1. What factors affect this relationship?
3. What is the effect of indicators of exposure or body stores on functional or clinical outcomes? (Curve 3 in diagram)
   1. What factors affect this relationship?
4. What is the effect of exposures on indicators of exposure or body stores? (Curve 4 in diagram)
   1. What factors affect this relationship?
5. What is the effect of indicators of exposure or body stores and intermediate indicators of outcomes? (Curve 5 in diagram)
   1. What factors affect this relationship?
6. What is the effect of intermediate indicators of outcomes and functional or clinical outcomes? (Curve 6 in diagram)
   1. What factors affect this relationship?

Note: Each question should include information with relevance to considerations of both benefit (efficacy) and safety (adverse effects).

*To be addressed in the evidence report.

Current as of October 2008

Internet Citation:

The Relationships of Vitamin D and Calcium Intakes to Nutrient Status Indicators and Health Outcomes, Clinical Focus. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/tp/vitadcaltp.htm